Inflammation & Chronic Migraine
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Key Questions
- ¿Qué papel juega la inflamación en la migraña crónica y otras enfermedades sistémicas?
- ¿Qué son los trastornos autoinmunes y cómo están relacionados con la inflamación?
- ¿Existen trastornos autoinmunes que sean comórbidos con la migraña?
- ¿Se considera la migraña un trastorno autoinmune?
- ¿Existen biomarcadores claros que indiquen inflamación?
- ¿Qué comportamientos de estilo de vida pueden ayudar a reducir la inflamación?
- ¿Qué es la sensibilización central?
- ¿Quién debería considerar hacerse pruebas de marcadores inflamatorios o condiciones autoinmunes?
- ¿Puede la neuromodulación ayudar a reducir la inflamación?
Interview Notes
- Gretchen E. Tietjen, MD
- American Headache Society
- Study: “Chemokine levels in the jugular venous blood of migraine without aura patients during attacks”
- Study: “Endogenous glucocorticoids may serve as biomarkers for migraine chronification”
- Study: “Diabetes is associated with decreased migraine risk: A nationwide cohort study”
- Andrew Charles, MD, director of the UCLA Goldberg Migraine Program
- Dan Levy, PhD, MSc, Associate Professor of Anesthesia, Beth Israel Deaconess Medical Center
Treatments Mentioned
- Acupuncture
- C-reactive protein (CRP) test
- Erythrocyte sedimentation rate (ESR) test
- Exercise
- Ice packs
- Indomethacin
- Mediterranean diet
- Neuromodulation devices
- Omega-3s
- Sleep
- Stress management
- Vagus (vagal) nerve stimulation
Please note: The Migraine World Summit’s aim is to bring you a variety of perspectives and expertise, independent of bias or judgment. Alternative theories presented in this video have not been medically reviewed. Views expressed in this interview do not necessarily represent the views of the Migraine World Summit. Please always consult your health care professional and do your own research before making changes to your treatment plan.
This is a Spanish translation of an expert interview from the Migraine World Summit 2024. All interviews have been carefully translated and medically reviewed.
Gretchen E. Tietjen, MD
Professor Emerita of Neurology
University of Toledo
Dr. Gretchen E. Tietjen is a graduate of the University of Michigan Medical School and its neurology residency program. She is a Distinguished University Professor Emerita of neurology at the University of Toledo, where she founded the Department of Neurology in 2000 and led as chair until 2020.
Specializing in headache medicine and vascular neurology, she also directed the Stroke Center for 15 years and the Headache Treatment and Research Center for over two decades. Her research focuses on the relationship between migraine and stroke, including the investigation of the vascular biology in migraine, the association of childhood maltreatment and migraine, and the effects of early life stress on vascular and brain biology in a rodent model.
Dr. Tietjen has published over 160 peer-reviewed papers, book chapters, reviews, and editorials. Her research has garnered national awards, including the Stroke Innovation Award from the journal Stroke and the Association of Migraine Disorders Innovation Award, as well as the American Headache Society’s Seymour Solomon Lecture Award, the Harold G. Wolff Lecture Award, the John R. Graham Lecture Award, the Women’s Health Research Lecture Award, and the 2022 Lifetime Achievement Award from the AHS.
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