Could Biomarkers Improve Migraine Diagnosis?
Key Questions
- ¿Qué es un biomarcador?
- ¿Cómo pueden identificarse los biomarcadores y cuáles biomarcadores posibles se han identificado para la migraña?
- ¿Están vinculados los ataques mediados por CGRP a tipos específicos de migraña?
- ¿Qué otras enfermedades tienen biomarcadores?
- ¿Cómo contribuye la neuroimagen a nuestra comprensión de los biomarcadores de la migraña y la migraña crónica versus episódica?
- ¿Se está reduciendo la materia gris en pacientes con migraña crónica?
- ¿Son los pacientes con migraña crónica más vulnerables a otros tipos de dolor no relacionados con la migraña?
- ¿Son reversibles los cambios en el cerebro causados por la migraña crónica?
- ¿Cuán lejos estamos de tener medicamentos basados en el péptido activador de la adenilato ciclasa pituitaria (PACAP) y su papel en la migraña?
- ¿Existen otros posibles biomarcadores para la migraña además de CGRP y PACAP?
- ¿Qué papel juegan la epigenética en la migraña y los biomarcadores?
- ¿Qué tan cerca estamos de desarrollar un biomarcador capaz de diagnosticar la migraña, identificar tipos específicos de migraña y guiar elecciones de tratamiento personalizadas?
- ¿Los biomarcadores reducen el estigma en torno a la migraña?
Interview Notes
- Study: “How does the brain change in chronic migraine? Developing disease biomarkers”
- Study: “Biomarkers of migraine: An integrated evaluation of preclinical and clinical findings”
- midolordeabceza.org
Treatments Mentioned
- CGRP inhibitors
Please note: The Migraine World Summit’s aim is to bring you a variety of perspectives and expertise, independent of bias or judgment. Alternative theories presented in this video have not been medically reviewed. Views expressed in this interview do not necessarily represent the views of the Migraine World Summit. Please always consult your health care professional and do your own research before making changes to your treatment plan.
This is a Spanish translation of an expert interview from the Migraine World Summit 2024. All interviews have been carefully translated and medically reviewed.
Patricia Pozo-Rosich, MD, PhD
Head of Neurology Section
Vall d’Hebron Hospital and Institute of Research, Spain
As the director of headache and neurological pain research at Vall d’Hebron Institute of Research in Barcelona, Spain, Dr. Pozo-Rosich is one of the leading migraine researchers in Europe. An active leader in the field of international headache medicine, Dr. Pozo-Rosich is passionate about educating patients and clinicians about migraine. She is the coordinator of the Headache Study Group of the Spanish Neurological Society (GECSEN). Additionally, she is the founder of the Spanish-language website MiDolordeCabeza.org. In 2023, she was awarded the Cephalalgia Award for her article “Salivary CGRP Can Monitor the Different Migraine Phases: CGRP (In)dependent Attacks,” which she presented at the International Headache Congress in Seoul, Korea.
Dr. Pozo-Rosich is a member of the International Headache Society, the American Headache Society, the International Headache Genetics Consortium, and the Catalan Neurological Society.
Interviews from Patricia Pozo-Rosich, MD, PhD
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