Unofficial Side Effects of CGRP Monoclonal Antibodies
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Key Questions
- ¿Qué son los inhibidores del péptido relacionado con el gen de la calcitonina (CGRP) y cómo funcionan?
- ¿Cuál es el “mecanismo de acción” en los inhibidores de CGRP?
- ¿Qué medicamentos inhibidores de CGRP están disponibles actualmente?
- ¿Qué son los anticuerpos monoclonales (mAbs) de CGRP?
- ¿Cuáles son los efectos secundarios más comunes de los inhibidores de CGRP reportados en ensayos clínicos?
- ¿Qué efectos secundarios de estos medicamentos se ven comúnmente en el uso práctico?
- ¿Cómo difieren los efectos secundarios de los eventos adversos?
- ¿El aumento de peso, la pérdida de cabello y los problemas gastrointestinales son efectos secundarios comunes de todos los mAbs de CGRP?
- ¿Los mAbs de CGRP pueden afectar los niveles de ánimo y ansiedad?
- ¿Los mAbs de CGRP pueden afectar la densidad ósea?
- ¿El CGRP juega un papel en nuestro sistema inmunológico?
- ¿Existen riesgos o efectos secundarios conocidos al combinar inhibidores de CGRP con otros medicamentos?
- ¿Qué debería hacer alguien si experimenta efectos secundarios de su medicamento?
Interview Notes
- Robert P. Cowan, MD, FAAN, FAHS
- EudraVigilance (European Medicines Agency)
- FDA MedWatch (or 800-438-1985)
- Food and Drug Administration (FDA)
- NHS (side effect reporting)
Treatments Mentioned
- Atogepant (Qulipta)
- CGRP inhibitors
- CGRP monoclonal antibodies (mAbs)
- CGRP small-molecule receptor antagonists (gepants)
- Eptinezumab (Vypeti)
- Erenumab (Aimovig)
- Fremanezumab (Ajovy)
- Galcanezumab (Emgality)
- Laxatives
- Topiramate (Topamax)
- Triptans
Please note: The Migraine World Summit’s aim is to bring you a variety of perspectives and expertise, independent of bias or judgment. Alternative theories presented in this video have not been medically reviewed. Views expressed in this interview do not necessarily represent the views of the Migraine World Summit. Please always consult your health care professional and do your own research before making changes to your treatment plan.
This is a Spanish translation of an expert interview from the Migraine World Summit 2024. All interviews have been carefully translated and medically reviewed.
Robert P. Cowan, MD
Professor of Neurology & Director of Research in Headache and Facial Pain
Stanford University School of Medicine
Dr. Robert P. Cowan is a clinical professor of neurology and director of the Stanford Headache and Facial Pain Program Research division at Stanford University. He is board certified in neurology and pain medicine with a subspecialty certification in headache medicine. Dr. Cowan has held several nationally elected positions, including chair of multiple sections for the American Headache Society (AHS).
He is the past president of the Headache Cooperative of the Pacific and was the founding chief of the headache division in the Department of Neurology at Stanford, and before that, at the Keck School of Medicine of USC. He is a fellow of the American Academy of Neurology and the American Headache Society. He has served on the boards of the Alliance for Headache Disorders Advocacy and the now-defunct American Headache and Migraine Association. He has published over 200 articles, chapters, abstracts, and posters and is the author of The Keeler Migraine Method.
Interviews from Robert P. Cowan, MD
Unofficial Side Effects of CGRP Monoclonal Antibodies
Long-Term Effects of New Migraine Medications
Why Most Doctors Get the Diagnosis Wrong
Best Natural, Affordable and Free Treatments
Migraine Causes & Triggers
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